The incident occurred around 3:25 PM on November 26, 2025, on the eastbound side of State Route 52 near Santo Road in San Diego.
San Diego, CA – At least one person was seriously injured after a two-vehicle collision involving a motorcycle on SR-52 East near Santo Road on Wednesday afternoon, according to the California Highway Patrol.
The incident occurred around 3:25 PM on November 26, 2025, on the eastbound side of State Route 52 near Santo Road in San Diego.
CHP dispatch logs indicate that two vehicles were involved, including a Kawasaki Ninja motorcycle. Responding units located the vehicles on the right-hand shoulder shortly after arriving.
One individual suffered major injuries with possible broken ribs. Emergency crews assessed the victim at the scene before transporting them to a nearby hospital.
A tow truck was requested at 3:42 PM to remove the motorcycle. By 4:05 PM, the Freeway Service Patrol reported the incident cleared, and lanes were reopened to normal traffic. Motorists traveling through the intersection area experienced delays during the response and cleanup.
The cause of the collision remains under investigation. CHP has not released information regarding contributing factors or fault.
San Diego County Motorcycle Accidents
Over the past few years, San Diego County has consistently ranked among the top counties in California for serious motorcycle crashes. In 2022, the county recorded 50 fatal motorcycle crashes — placing it among the top five counties statewide for motorcycle‑related deaths.
Meanwhile, in 2023, it was reported that 56 motorcyclists died in crashes in San Diego County.
In addition to the fatalities, San Diego also had a high number of serious nonfatal injuries from motorcycle crashes: in 2022 it ranked second in California for serious motorcycle‑related injuries, with 348 serious injury cases, according to Safe Trans Research Centre.
Those numbers reflect a broader pattern: motorcycles — while forming a fraction of total vehicles — continue to be disproportionately involved in severe and fatal collisions. Statewide in California (and by extension in populous counties like San Diego), motorcyclists accounted for 14% of all motor‑vehicle fatalities in 2022.
If you or a loved one has been injured in this San Diego Motorcycle collision, you can learn more about your options by visiting our San Diego Personal Injury Attorney page.